Tohoku University Technology: Lactic Acid Bacteria that Improve Mitochondrial Function: T23-024
Aim to prevent various diseases through daily meals.
Mitochondria, responsible for energy production, increase the production of reactive oxygen species (ROS) when their function declines. ROS is associated with the onset and worsening of diseases such as neurodegenerative disorders, diabetes, and cancer. Notably, the decline in mitochondrial activity in intestinal epithelial cells has been shown to be related to diseases not only in the intestines but also throughout the body. Until now, there have been no examples of simultaneously analyzing multiple food components that affect mitochondrial function in intestinal epithelial cells. The inventors established a method to detect components that have the effect of suppressing ROS production using porcine intestinal epithelial cells and conducted screenings. As a result, they revealed that FFIG35 (Ligilactobacillus salivarius), a type of lactic acid bacteria held in their laboratory, suppresses ROS production and improves cellular oxygen consumption and ATP production. It is expected that consuming food mixed with the above lactic acid bacteria will help prevent various diseases and extend healthy lifespan. Additionally, due to the mechanism of acting on the epithelium to improve mitochondrial function, there is potential for use as topical agents (such as cosmetics and bath additives).
- Company：Tohoku Techno Arch Co., Ltd.
- Price：Other
